Article
Risk stratification using FLT3 and NPM1 in acute myeloid leukemia patients autografted in first complete remission.
Bone marrow transplantation - 1 Dec 2020
Shouval Roni, Labopin Myriam, Bomze David, Baerlocher Gabriela M, Capria Saveria, Blaise Didier, Hänel Mathias, Forcade Edouard, Huynh Anne, Saccardi Riccardo, Milone Giuseppe, Zuckerman Tsila, Reményi Péter, Versluis Jurjen, Esteve Jordi, Gorin Norbert Claude, Mohty Mohamad, Nagler Arnon
Abstract excerpt
FLT3-ITD and NPM1 mutation refine prognostic stratification in acute myeloid leukemia (AML) with intermediate-risk cytogenetics. However, data on their role in patients undergoing autologous stem cell transplantation (Auto-SCT) as post-remission therapy (PRT) are limited. We therefore sought to retrospectively evaluate the role of FLT3-ITD and NPM1 in a cohort of AML patients (n = 405) with intermediate-risk...
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