Article
Redefining epithelial progenitor potential in the developing thymus.
European journal of immunology - 1 Sept 2007
Rossi Simona W, Chidgey Ann P, Parnell Sonia M, Jenkinson William E, Scott Hamish S, Boyd Richard L, Jenkinson Eric J, Anderson Graham
Abstract excerpt
Cortical and medullary epithelium represent specialised cell types that play key roles in thymocyte development, including positive and negative selection of the T cell repertoire. While recent evidence shows that these epithelial lineages share a common embryonic origin, the phenotype and possible persistence of such progenitor cells in the thymus at later stages of development remain controversial. Through use...
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