Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Thymocyte subpopulation enriched for progenitors with an unrearranged T-cell receptor beta-chain gene.

Nature - 1 Jan 2000

Trowbridge I S, Lesley J, Trotter J, Hyman R

Abstract excerpt

The development of T cells within the thymus is not well understood. It is known that thymocytes are derived from a progenitor cell in the bone marrow, the prothymocyte, and that cells in the subcapsular area of the thymus can give rise to progeny in both the cortex and the medulla. However, it is not clear whether all medullary thymocytes are necessarily derived from cortical cells. In particular, it has been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Separation
Share to Genes
Share to Mice

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Phenotype

Share to Receptors, Antigen, T-Cell

Share to Receptors, Immunologic

Share to Stem Cells

Share to T-Lymphocytes

Source

Identifiers

PMID: 3874369
DOI: 10.1038/315666a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Thymocyte subpopulation enriched for progenitors with an unrearranged T-cell receptor beta-chain gene.PMID 3874369Read ↗

Differentiation potential of subsets of CD4-8- thymocytes.Semantic proximity Read ↗

Identification and characterization of pro-T lymphocytes and lineage-uncommitted lymphocyte precursors from mice with three novel surface markers.Semantic proximity Read ↗

A novel population of T-cell receptor alpha beta-bearing thymocytes which predominantly expresses a single V beta gene family.Semantic proximity Read ↗

TCR Gene Rearrangements and Expression of the Pre-T Cell Receptor Complex During Human T-Cell DifferentiationSemantic proximity Read ↗

Phenotypic plasticity of T cell progenitors upon exposure to Notch ligands.Semantic proximity Read ↗

Normal sequence of phenotypic transitions in one cohort of 5-bromo-2'-deoxyuridine-pulse-labeled thymocytes. Correlation with T cell receptor expression.Semantic proximity Read ↗

A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors.Semantic proximity Read ↗

Identification of a novel human thymocyte subset with a phenotype of CD3- CD4+ CD8 alpha + beta-1. Possible progeny of the CD3- CD4- CD8- subset.Semantic proximity Read ↗

Two groups of porcine TCRgammadelta+ thymocytes behave and diverge differently.Semantic proximity Read ↗

CD45RA antibodies split the CD3bright T cell subset.Semantic proximity Read ↗

T cell receptor-mediated selection of functional rat CD8 T cells from defined immature thymocyte precursors in short-term suspension culture.Semantic proximity Read ↗

Regulation of N-region diversity in antigen receptors through thymocyte differentiation and thymus ontogeny.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.