Article
Fc gamma RII/III and CD2 expression mark distinct subpopulations of immature CD4-CD8- murine thymocytes: in vivo developmental kinetics and T cell receptor beta chain rearrangement status.
The Journal of experimental medicine - 1 Apr 1993
Rodewald H R, Awad K, Moingeon P, D'Adamio L, Rabinowitz D, Shinkai Y, Alt F W, Reinherz E L
Abstract excerpt
We have recently identified a dominant wave of CD4-CD8- (double-negative [DN]) thymocytes in early murine fetal development that express low affinity Fc gamma receptors (Fc gamma RII/III) and contain precursors for Ti alpha/beta lineage T cells. Here we show that Fc gamma RII/III is expressed in...
Topics
- Aging
- Animals
- Antigens, Differentiation, T-Lymphocyte
- Base Sequence
- CD2 Antigens
- CD4 Antigens
- CD8 Antigens
- Cell Cycle
- Cell Separation
- DNA
- Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
- Mice
- Mice, Inbred C57BL
- Molecular Sequence Data