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Article

Transforming growth factor-β and myostatin signaling in skeletal muscle

21 Nov 2007

Abstract excerpt

The superfamily of transforming growth factor-beta (TGF-beta) cytokines has been shown to have profound effects on cellular proliferation, differentiation, and growth. Recently, there have been major advances in our understanding of the signaling pathway(s) conveying TGF-beta signals to the nucleus to ultimately control gene expression. One tissue that is potently influenced by TGF-beta superfamily signaling is...

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PMID: 18032576
DOI: 10.1152/japplphysiol.01091.2007

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