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CDKN3 promotes tumor progression and confers cisplatin resistance via RAD51 in esophageal cancer

1 Apr 2019

Abstract excerpt

Purpose: Esophageal cancer (ESCA) progression and chemoresistance are critical factors that impact the survival of patients with esophageal cancer. Cyclin dependent kinase inhibitor 3 (CDKN3) is an important regulator of the cell cycle that has received little attention, therefore the purpose of this study was to investigate CDKN3 involvement in ESCA. Methods: We first explored the public database in addition to...

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PMID: 31114363
DOI: 10.2147/cmar.s193793

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