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Article

Clinical Outcome-Related Cancer Pathways and Mutational Signatures in Patients With Unresectable Esophageal Squamous Cell Carcinoma Treated With Chemoradiotherapy.

International journal of radiation oncology, biology, physics - 1 Feb 2023

Li Li, Sun Jujie, Liu Ning, Yu Ruoying, Zhang Junli, Pang Jiaohui, Ou Qiuxiang, Yin Ying, Cui Jinfeng, Yao Xuling, Zhao Ranran, Shao Yang, Yuan Shuanghu, Yu Jinming

Abstract excerpt

PURPOSE: Definitive chemoradiotherapy (dCRT) is a standard-of-care for locally advanced unresectable esophageal squamous cell carcinoma (ESCC). However, even in individuals treated with the same dCRT regimen, differences in the local control rate and radiation-induced thoracic toxicity exist (radiation-induced esophagitis [RIE]). METHODS AND MATERIALS: Here, we describe a comprehensive genomic evaluation of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 36167753
DOI: 10.1016/j.ijrobp.2022.07.1835

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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