Article

FOXK1 regulates malignant progression and radiosensitivity through direct transcriptional activation of CDC25A and CDK4 in esophageal squamous cell carcinoma

2022-12-19

Abstract excerpt

The transcription factor forkhead box K1 (FOXK1) has recently been recognized to mediate a wide range of biological progresses, including cell proliferation, differentiation, cell cycle progression, apoptosis, DNA damage, and tumorigenesis. However, the role and molecular mechanisms of FOXK1 in esophageal squamous cell carcinoma (ESCC) progression and in the response to ionizing radiation (IR) have not been well c...

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Literature Corpus work: 91505a25-9023-53dd-902c-f3278370a47e
DOI: 10.21203/rs.3.rs-2368026/v1

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