Article
Downregulation of miR-503 Promotes ESCC Cell Proliferation, Migration, and Invasion by Targeting Cyclin D1.
Genomics, proteomics & bioinformatics - 1 Jun 2017
Jiang Lanfang, Zhao Zitong, Zheng Leilei, Xue Liyan, Zhan Qimin, Song Yongmei
Abstract excerpt
Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive cancers in China, but the underlying molecular mechanism of ESCC is still unclear. Involvement of microRNAs has been demonstrated in cancer initiation and progression. Despite the reported function of miR-503 in several human cancers, its detailed anti-oncogenic role and clinical significance in ESCC remain undefined. In this study, we...
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