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Article

Molecular mechanisms associated with chemoresistance in esophageal cancer.

Cellular and molecular life sciences : CMLS - 3 Feb 2022

Lohan-Codeço Matheus, Barambo-Wagner Maria Luísa, Nasciutti Luiz Eurico, Ribeiro Pinto Luis Felipe, Meireles Da Costa Nathalia, Palumbo Antonio

Abstract excerpt

Esophageal cancer (EC) is one of the most incident and lethal tumors worldwide. Although surgical resection is an important approach in EC treatment, late diagnosis, metastasis and recurrence after surgery have led to the management of adjuvant and neoadjuvant therapies over the past few decades. In this scenario, 5-fluorouracil (5-FU) and cisplatin (CISP), and more recently paclitaxel (PTX) and carboplatin...

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Identifiers

PMID: 35113247
DOI: 10.1007/s00018-022-04131-6
PMCID: PMC11073146

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