Article

NEK2 Promotes the Migration, Invasion, Proliferation and Drug Resistance of ESCC Through the E2F1-IGF2 Pathway

2023-01-24

Abstract excerpt

<h4>Purpose: </h4> Esophageal squamous cell carcinoma(ESCC) is a disease with a high incidence rate and high mortality worldwide. The Never in Mitosis A (NIMA) family member NIMA-related kinase 2 (NEK2) plays an important role in mitosis. However, the role of NEK2 in the pathogenesis of ESCC remains unclear. Patients and methods: The expression and function of NEK2 in TCGA and GEO data sets were analyzed by bioin...

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Literature Corpus work: 67c90eaf-e847-540c-afbb-c975335257e3
DOI: 10.21203/rs.3.rs-2489675/v1

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