Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Recent Progress on the Discovery of Sirt2 Inhibitors for the Treatment of Various Cancers

10 May 2019

Abstract excerpt

Sirtuins family is a class of NDA+ dependent protein deacetylases that play a key role in the regulation of several aspects of biological processes, such as cell cycle regulation, autophagy, immune and inflammatory response. Many studies have shown that sirtuins2 as a key player in the cancer pathway is of great significance in tumorigenesis. This review summarizes the newly discovered, in recent years, some...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to PARP inhibition in cancer therapy
Share to Sirtuins and Resveratrol in Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31074370
DOI: 10.2174/1568026619666190510103416

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Recent Progress on the Discovery of Sirt2 Inhibitors for the Treatment of Various CancersPMID 31074370Read ↗

Structure, functions, and recent advances in the development of SIRT2 inhibitorsSemantic proximity Read ↗

Rejuvenating Sirtuins: The Rise of a New Family of Cancer Drug TargetsSemantic proximity Read ↗

The Roles of Sirtuin Family Proteins in Cancer ProgressionSemantic proximity Read ↗

The role of SIRT2 in cancer: A novel therapeutic targetSemantic proximity Read ↗

The emerging and diverse roles of sirtuins in cancer: a clinical perspectiveSemantic proximity Read ↗

Sirtuin functions and modulation: from chemistry to the clinicSemantic proximity Read ↗

Targeting sirtuins for cancer therapy: epigenetics modifications and beyondSemantic proximity Read ↗

The sirtuin family in health and diseaseSemantic proximity Read ↗

Advances in Cellular Characterization of the Sirtuin Isoform, SIRT7Semantic proximity Read ↗

Human Sirtuin 2 inhibitors, Their Mechanisms and Binding ModesSemantic proximity Read ↗

Biological and Potential Therapeutic Roles of Sirtuin DeacetylasesSemantic proximity Read ↗

The Biochemistry of SirtuinsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.