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Article

Genomics and transcriptomic alterations of the glutamate receptors in acute myeloid leukemia.

Clinical and translational science - 1 Oct 2023

Alqahtani Amani, Wang Mengxi, Lou Mimi, Alachkar Houda

Abstract excerpt

Glutamine and glutamate have been widely explored as potential therapeutic targets in acute myeloid leukemia (AML). In addition to its bioenergetic role in leukemia cell proliferation, L-glutamate is a neurotransmitter that acts on glutamate receptors. However, the role of glutamate receptors in AML is largely understudied. Here, we comprehensively analyze the genomic and transcriptomic alterations of glutamate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37670476
DOI: 10.1111/cts.13588
PMCID: PMC10582680

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