Article
Silencing of selected glutamate receptor subunits modulates cancer growth.
Anticancer research - 1 Oct 2011
Luksch Hella, Uckermann Ortrud, Stepulak Andrzej, Hendruschk Sandy, Marzahn Jenny, Bastian Susanne, Staufner Christian, Temme Achim, Ikonomidou Chrysanthy
Abstract excerpt
BACKGROUND: Emerging evidence supports a role for glutamate in the biology of cancer. We studied the impact of glutamate receptor subunit silencing on cancer phenotype. MATERIALS AND METHODS: Different fragments of the coding region for ionotropic glutamate receptor AMPA 4 (GLUR4), ionotropic glutamate receptor N-methyl D-aspartate 1 (NR1), ionotropic glutamate receptor kainate 5 (KA2) and ionotropic glutamate...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
