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Article

Genetic and observational evidence supports a causal role of sex hormones on the development of asthma

1 Apr 2019

Abstract excerpt

INTRODUCTION: Males have a higher prevalence of asthma in childhood, whereas females have a higher prevalence in adolescence and adulthood. The 'adolescent switch' observed between sexes during puberty has been hypothesised to be due to fluctuating sex hormones. Robust evidence of the involvement of sex hormones in asthma could lead to development of therapeutic interventions. METHODS: We combine observational...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30936389
DOI: 10.1136/thoraxjnl-2018-212207

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