Article
Zinc finger protein 33B demonstrates sex interaction with atopy-related markers in childhood asthma.
The European respiratory journal - 1 Jan 2023
Lee Sanghun, Prokopenko Dmitry, Kelly Rachel S, Lutz Sharon, Ann Lasky-Su Jessica, Cho Michael H, Laurie Cecelia, Celedón Juan C, Lange Christoph, Weiss Scott T, Hecker Julian, DeMeo Dawn L
Abstract excerpt
BACKGROUND: Sex differences related to immune responses can influence atopic manifestations in childhood asthma. While genome-wide association studies have investigated a sex-specific genetic architecture of the immune response, gene-by-sex interactions have not been extensively analysed for atopy-related markers including allergy skin tests, IgE and eosinophils in asthmatic children. METHODS: We performed a...
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