Article
Genomic architecture of asthma differs by sex.
Genomics - 1 Jul 2015
Mersha Tesfaye B, Martin Lisa J, Biagini Myers Jocelyn M, Kovacic Melinda Butsch, He Hua, Lindsey Mark, Sivaprasad Umasundari, Chen Weiguo, Khurana Hershey Gurjit K
Abstract excerpt
Asthma comprised of highly heterogeneous subphenotypes resulting from complex interplay between genetic and environmental stimuli. While much focus has been placed on extrinsic environmental stimuli, intrinsic environment such as sex can interact with genes to influence asthma risk. However, few studies have examined sex-specific genetic effects. The overall objective of this study was to evaluate if sex-based...
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