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Article

Sex-biased Gene Expression Underlies Immune Dysfunction in Asthma

30 Jun 2025

Abstract excerpt

Abstract Asthma prevalence and severity differs between male and female individuals across the lifespan. Prepubescent boys are more likely to experience asthma, but girls are disproportionately affected after puberty, with greater symptom burden and decreased type 2 inflammation. However, because the human male and female genomes are almost identical, it is especially difficult to identify differentially...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 40587876
DOI: 10.1165/rcmb.2024-0565oc

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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