Genome-wide interaction studies reveal sex-specific asthma risk alleles.

doi:10.1093/hmg/ddu222

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Article

Genome-wide interaction studies reveal sex-specific asthma risk alleles.

Human molecular genetics - 1 Oct 2014

Myers Rachel A, Scott Nicole M, Gauderman W James, Qiu Weiliang, Mathias Rasika A, Romieu Isabelle, Levin Albert M, Pino-Yanes Maria, Graves Penelope E, Villarreal Albino Barraza, Beaty Terri H, Carey Vincent J, Croteau-Chonka Damien C, del Rio Navarro Blanca, Edlund Christopher, Hernandez-Cadena Leticia, Navarro-Olivos Efrain, Padhukasahasram Badri, Salam Muhammad T, Torgerson Dara G, Van den Berg David J, Vora Hita, Bleecker Eugene R, Meyers Deborah A, Williams L Keoki, Martinez Fernando D, Burchard Esteban G, Barnes Kathleen C, Gilliland Frank D, Weiss Scott T, London Stephanie J, Raby Benjamin A, Ober Carole, Nicolae Dan L

Abstract excerpt

Asthma is a complex disease with sex-specific differences in prevalence. Candidate gene studies have suggested that genotype-by-sex interaction effects on asthma risk exist, but this has not yet been explored at a genome-wide level. We aimed to identify sex-specific asthma risk alleles by performing a genome-wide scan for genotype-by-sex interactions in the ethnically diverse participants in the EVE Asthma...

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Identifiers

PMID: 24824216
DOI: 10.1093/hmg/ddu222
PMCID: PMC4159149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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