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Article

Identification of IDH-mutant gliomas by a prognostic signature according to gene expression profiling.

Aging - 15 Aug 2018

Wang Qiangwei, Wang Zhiliang, Li Guanzhang, Zhang Chuanbao, Bao Zhaoshi, Wang Zheng, You Gan, Jiang Tao

Abstract excerpt

BACKGROUND: Isocitrate dehydrogenase (IDH) mutations are the most common genetic aberrations in gliomagenesis. We aimed to build a high-efficiency prediction gene signature in patients with IDH-mutant glioma. METHODS: In total, 167 gliomas from Chinese Glioma Genome Atlas (CGGA) dataset were included for discovery. The Cancer Genome Atlas (TCGA) dataset was used for validation. R language was the main software...

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Identifiers

PMID: 30115812
DOI: 10.18632/aging.101521
PMCID: PMC6128431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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