Article
Polygenic risk prediction models for colorectal cancer: a systematic review.
BMC cancer - 15 Jan 2022
Sassano Michele, Mariani Marco, Quaranta Gianluigi, Pastorino Roberta, Boccia Stefania
Abstract excerpt
BACKGROUND: Risk prediction models incorporating single nucleotide polymorphisms (SNPs) could lead to individualized prevention of colorectal cancer (CRC). However, the added value of incorporating SNPs into models with only traditional risk factors is still not clear. Hence, our primary aim was to summarize literature on risk prediction models including genetic variants for CRC, while our secondary aim was to...
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