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Article

KRAS G12V Mutation is an Adverse Prognostic Factor of Chinese Gastric Cancer Patients

1 Jan 2019

Abstract excerpt

This study aims to investigate the molecular characteristics of Chinese gastric cancer patients. In our study, the KRAS, BRAF, and PIK3CA mutation status of 485 GC patients were analyzed by Sanger sequencing. Kaplan-Meier analysis was used to plot survival curves according to different genotypes. The results show that the frequency of KRAS, BRAF and PIK3CA mutations were 4.1%, 1.2% and 3.5%, respectively. BRAF...

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PMID: 30854087
DOI: 10.7150/jca.27899

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