Article
KRAS Mutation in Gastric Cancer and Prognostication Associated with Microsatellite Instability Status.
Pathology oncology research : POR - 1 Jan 2019
Polom Karol, Das Kakoli, Marrelli Daniele, Roviello Giandomenico, Pascale Valeria, Voglino Costantino, Rho Henry, Tan Patrick, Roviello Franco
Abstract excerpt
Microsatellite instability (MSI) is one of the subgroups based on the new molecular classification of gastric cancer (GC). In this study, we analyzed the role of KRAS status in MSI GC and the impact of MSI status on KRAS mutation. We performed analysis on 595 GC patients. Polymerase chain reaction (PCR) was used for the screening of KRAS mutation (exon 2) and 5 quasi-monomorphic mononucleotide repeats, namely,...
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