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Article

BRAF V600E mutation and KRAS codon 13 mutations predict poor survival in Chinese colorectal cancer patients.

BMC cancer - 3 Nov 2014

Chen Jing, Guo Fang, Shi Xin, Zhang Lihua, Zhang Aifeng, Jin Hui, He Youji

Abstract excerpt

BACKGROUND: Mutations in KRAS, BRAF and PIK3CA are the most common somatic alterations found in the colorectal cancer (CRC) patients from Western countries; but their prevalence and prognostic value have not been adequately assessed in Asian patients. The aim of this study was to determine the mutation frequencies of these genes in Chinese CRC patients and to investigate their impact on prognosis. METHODS: The...

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Identifiers

PMID: 25367198
DOI: 10.1186/1471-2407-14-802
PMCID: PMC4233032

Genes

BRAF
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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