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Article

Mutations in BRAF correlate with poor survival of colorectal cancers in Chinese population.

International journal of colorectal disease - 1 Nov 2011

Liou Jyh-Ming, Wu Ming-Shiang, Shun Chia-Tung, Chiu Han-Mo, Chen Mei-Jyh, Chen Chien-Chuan, Wang Hsiu-Po, Lin Jaw-Town, Liang Jin-Tung

Abstract excerpt

PURPOSE: Mutations in KRAS and BRAF genes were associated with treatment failure from EGF receptor inhibitors in colorectal cancer (CRC) patients. However, whether these mutations were associated with survival in patients not treated with EGF receptor inhibitors remained controversial. Moreover, few data were available in Chinese. Therefore, we aimed to evaluate the impact of KRAS and BRAF mutations on the...

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Source

Identifiers

PMID: 21553007
DOI: 10.1007/s00384-011-1229-1

Genes

BRAF
KRAS
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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