A let-7 binding site polymorphism rs712 in the KRAS 3' UTR is associated with an increased risk of gastric cancer.

doi:10.1007/s13277-013-0885-x

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Article

A let-7 binding site polymorphism rs712 in the KRAS 3' UTR is associated with an increased risk of gastric cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2013

Li Zhao-Hui, Pan Xin-Min, Han Bao-Wei, Guo Xiao-Min, Zhang Zhen, Jia Jing, Gao Lin-Bo

Abstract excerpt

Recently, single nucleotide polymorphisms in let-7 miRNA binding site in 3' untranslated region (UTR) of KRAS mRNA have been found to be associated with the cancer risk. In this study, we genotyped the frequency of KRAS rs712 to test its effect on gastric cancer (GC) risk in a hospital-based case-control study in a Chinese population, with 181 histologically confirmed GC patients and 674 cancer-free controls,...

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PMID: 23729275
DOI: 10.1007/s13277-013-0885-x

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KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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