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Genetic variation rs10484761 on 6p21.1 derived from a genome-wide association study is associated with gastric cancer survival in a Chinese population.

Gene - 15 Feb 2014

Kang Meiyun, Ding Xiaojie, Xu Ming, Zhu Haixia, Liu Sang, Wang Meilin, Wu Dongmei, Tong Na, Gong Weida, Zhou Jianwei, Zhang Zhengdong

Abstract excerpt

A recent genome-wide association study (GWAS) on esophageal squamous-cell carcinoma (ESCC) among Chinese people has discovered a novel single nucleotide polymorphism (SNP) rs10484761 on 6p21.1 region. We hypothesized that SNP rs10484761 T/C is associated with survival of gastric cancer. We genotyped SNP rs10484761 in 940 gastric cancer patients treated with surgical resection. Kaplan-Meier survival analysis,...

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PMID: 24325909
DOI: 10.1016/j.gene.2013.11.087

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