Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular Support for Heterogonesis Resulting in Sesquizygotic Twinning

27 Feb 2019

Abstract excerpt

Sesquizygotic multiple pregnancy is an exceptional intermediate between monozygotic and dizygotic twinning. We report a monochorionic twin pregnancy with fetal sex discordance. Genotyping of amniotic fluid from each sac showed that the twins were maternally identical but chimerically shared 78% of their paternal genome, which makes them genetically in between monozygotic and dizygotic; they are sesquizygotic. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Assisted Reproductive Technology and Twin Pregnancy
Share to Genetic Syndromes and Imprinting
Share to Prenatal Screening and Diagnostics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30811910
DOI: 10.1056/nejmoa1701313

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular Support for Heterogonesis Resulting in Sesquizygotic TwinningPMID 30811910Read ↗

Whole-genome sequences reveal zygotic composition in chimeric twinsSemantic proximity Read ↗

The genetics of twinning: From splitting eggs to breaking paradigmsSemantic proximity Read ↗

Genetic and Epigenetic Mechanisms Underlying Phenotypic Discordance in Monochorionic Monozygotic Twins: A Systematic Review.Semantic proximity Read ↗

Non‐identical monozygotic twins, intermediate twin types, zygosity testing, and the non‐random nature of monozygotic twinning: A reviewSemantic proximity Read ↗

Blood ties: chimerism can mask twin discordance in high-throughput sequencing.Semantic proximity Read ↗

A characterization of postzygotic mutations identified in monozygotic twins.Semantic proximity Read ↗

Clinician-reported chorionicity and zygosity assignment using single-nucleotide polymorphism-based cell-free DNA: Lessons learned from 55,344 twin pregnancies.Semantic proximity Read ↗

A prenatal case misunderstood as specimen confusion: 46,XY/46,XY chimerism.Semantic proximity Read ↗

Clonal dynamics of monozygotic twinning in early human embryogenesisSemantic proximity Read ↗

Differences between germline genomes of monozygotic twins.Semantic proximity Read ↗

The genetic architecture of sporadic and multiple consecutive miscarriage.Semantic proximity Read ↗

Identical but not the same: the value of discordant monozygotic twins in genetic research.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.