Article
Identical but not the same: the value of discordant monozygotic twins in genetic research.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Sept 2010
Zwijnenburg Petra J G, Meijers-Heijboer Hanne, Boomsma Dorret I
Abstract excerpt
Monozygotic (MZ) twins show remarkable resemblance in many aspects of behavior, health, and disease. Until recently, MZ twins were usually called "genetically identical"; however, evidence for genetic and epigenetic differences within rare MZ twin pairs has accumulated. Here, we summarize the literature on MZ twins discordant for Mendelian inherited disorders and chromosomal abnormalities. A systematic literature...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
