Article
Blood ties: chimerism can mask twin discordance in high-throughput sequencing.
Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Apr 2011
Erlich Yaniv
Abstract excerpt
Twin studies have long provided a means to separate the contributions of genetic and environmental factors. A recent pioneering report by Baranzini et al. presented an analysis of the complete genomes and epigenomes of a monozygotic (MZ) twin pair discordant for multiple sclerosis. This failed to find any difference between the twins, raising doubts regarding the value of whole-genome twin studies for defining...
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