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Article

Radiotherapy resistance acquisition in Glioblastoma. Role of SOCS1 and SOCS3

27 Feb 2019

Abstract excerpt

Glioblastoma multiforme (GBM) is a poor prognosis type of tumour due to its resistance to chemo and radiotherapy. SOCS1 and SOCS3 have been associated with tumour progression and response to treatments in different kinds of cancers, including GBM. In this study, cell lines of IDH-wildtype GBM from primary cultures were obtained, and the role of SOCS1 and SOCS3 in the radiotherapy response was analysed. Fifty-two...

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PMID: 30811476
DOI: 10.1371/journal.pone.0212581

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