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Article

STAT3 as a Therapeutic Target for Glioblastoma

1 Sept 2010

Abstract excerpt

Glioblastoma (GBM) is the most common type of primary malignant brain tumor. Despite advances in surgical resection, radiotherapy and chemotherapy, prognosis remains very poor. Accordingly, recent studies have been focused on the aberrant signal transduction pathways in glioblastoma. Many patient derived primary glioblastomas and cell lines express constitutively activated signal transducers and activators of...

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PMID: 20879983
DOI: 10.2174/187152010793498636

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