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Non‐ossifying fibroma: A RAS‐MAPK driven benign bone neoplasm

27 Feb 2019

Abstract excerpt

Non-ossifying fibroma (NOF) has been an intriguing entity since its first description. It is the most common bone tumour, is usually asymptomatic affecting children and adolescents, is composed of a heterogeneous cell population, and undergoes spontaneous regression after puberty. In a recent article in The Journal of Pathology, Baumhoer and colleagues demonstrate mutations activating the RAS-MAPK pathway (KRAS,...

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PMID: 30809793
DOI: 10.1002/path.5259

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