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Article

Benign fibro-osseous lesions of the cranio-maxillofacial bones: an updated review with special emphasis on molecular pathogenesis.

Journal of bone and mineral metabolism - 1 Jan 2026

Pandiar Deepak, Krishnan Reshma Poothakulath, Gopinath Divya, Reddy Saravanan Sampoornam Pape, Veeraiyan Deepak Nallaswamy, Vijayakumar Goutham

Abstract excerpt

BACKGROUND: Benign fibro-osseous lesions (BFOLs) are a heterogeneous group of bone-forming pathologies characterized by replacement of normal bone with fibrocellular stroma and mineralized tissue. Their overlapping clinical, radiological, and histopathological features often complicate diagnosis. OBJECTIVE: This review summarizes the clinicopathologic characteristics and recent molecular insights of BFOLs to...

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PMID: 41249713
DOI: 10.1007/s00774-025-01662-3

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GNAS

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