KRAS mutations in brown tumor of the jaws in hyperparathyroidism.

doi:10.1111/jop.13048

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Article

KRAS mutations in brown tumor of the jaws in hyperparathyroidism.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Sept 2020

Guimarães Letícia Martins, Gomes Isadora Pereira, Pereira Thaís Dos Santos Fontes, de Andrade Bruno Augusto Benevenuto, Romañach Mário José, de Lacerda Júlio César Tanos, Pontes Hélder Antônio Rebelo, Brennan Peter A, Rahimi Siavash, Carlos Román, Mosqueda-Taylor Adalberto, Bologna-Molina Ronell, Passador-Santos Fabricio, Gomez Ricardo Santiago, Gomes Carolina Cavaliéri

Abstract excerpt

BACKGROUND: Brown tumors are giant cell-rich lesions that result from abnormal bone metabolism in hyperparathyroidism, one of the most common endocrine disorders worldwide. Brown tumors occasionally affect the jaws and, despite well-known clinical and microscopic features, their molecular pathogenesis remains unclear. We investigated the presence of pathogenic activating mutations in TRPV4, FGFR1, and KRAS in a...

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PMID: 32492752
DOI: 10.1111/jop.13048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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