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Article

Update on the molecular pathology of the distinctive giant cell, fibro-osseous and bone forming lesions of the jaws.

Seminars in diagnostic pathology - 1 Jul 2026

Guimarães Letícia Martins, Odell Edward W, Gomes Carolina Cavalieri

Abstract excerpt

In the 5th edition World Health Organisation (WHO) classification of head and neck tumours, lesions that are distinctive in the jaws for reasons of presentation, behaviour or molecular changes are separated from the bone tumour classification and listed with head and neck tumours in a section on odontogenic and maxillofacial bone tumours. The molecular characterisation of these lesions has advanced recently and...

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Identifiers

PMID: 42361776
DOI: 10.1016/j.semdp.2026.151031

Genes

KRAS
ANO5
FGFR1
GNAS
NFATC2
SATB2
SH3BP2
TRPV4
USP6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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