Article

Cemento-Osseous Dysplasia With a NOTCH4 Mutation: a Case Report

2025-06-04

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose</bold> Cemento-osseous dysplasia (COD) is a benign fibro-osseous lesion of the jaw that poses diagnostic challenges due to overlapping features with other entities, particularly cemento-ossifying fibroma (COF). While recent studies have identified mutations in the RAS-MAPK pathway in COD, its broader molecular profile remains poorly understood. Here, we report a case of CO...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e1237a5d-3076-560d-806d-b6c4902c3dbe
DOI: 10.21203/rs.3.rs-6689921/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Cemento-Osseous Dysplasia With a NOTCH4 Mutation: a Case ReportDOI 10.21203/rs.3.rs-6689921/v1Read

Benign fibro-osseous lesions of the cranio-maxillofacial bones: an updated review with special emphasis on molecular pathogenesis.Semantic proximity Read

Cemento-osseous dysplasia is caused by RAS-MAPK activation.Semantic proximity Read

Update on the molecular pathology of the distinctive giant cell, fibro-osseous and bone forming lesions of the jaws.Semantic proximity Read

Benign fibro-osseous lesions of the craniofacial complex. A review.Semantic proximity Read

Alterations of TGFBR2 and KRAS in cemento-osseous dysplasia of the jaw.Semantic proximity Read

Copy number alteration profiling facilitates differential diagnosis between ossifying fibroma and fibrous dysplasia of the jawsSemantic proximity Read

Update on the molecular pathology and classification of odontogenic cysts and tumours.Semantic proximity Read

Calcifying Odontogenic Cyst Demonstrates Recurrent WNT Pathway Mutations and So-Called Adenoid Ameloblastoma-Like Histology: Evidence Supporting Its Classification as a Neoplasm.Semantic proximity Read

Classification of Fibro-Osseous Tumors in the Craniofacial Bones Using DNA Methylation and Copy Number AlterationsSemantic proximity Read

Making sense of giant cell lesions of the jaws (GCLJ): lessons learned from next-generation sequencing.Semantic proximity Read

Exploring mutations: GNAS and CDC73 in jaw fibroosseous lesions.Semantic proximity Read

Fibrous dysplasia of the jaws: Integrating molecular pathogenesis with clinical, radiological, and histopathological featuresSemantic proximity Read