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Article

Modeling Heterogeneity in the Genetic Architecture of Ethnically Diverse Groups Using Random Effect Interaction Models.

Genetics - 1 Apr 2019

Veturi Yogasudha, de Los Campos Gustavo, Yi Nengjun, Huang Wen, Vazquez Ana I, Kühnel Brigitte

Abstract excerpt

In humans, most genome-wide association studies have been conducted using data from Caucasians and many of the reported findings have not replicated in other populations. This lack of replication may be due to statistical issues (small sample sizes or confounding) or perhaps more fundamentally to differences in the genetic architecture of traits between ethnically diverse subpopulations. What aspects of the...

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Identifiers

PMID: 30796011
DOI: 10.1534/genetics.119.301909
PMCID: PMC6456318

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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