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Article

The CRISPR-Cas immune system: biology, mechanisms and applications.

Biochimie - 1 Oct 2015

Rath Devashish, Amlinger Lina, Rath Archana, Lundgren Magnus

Abstract excerpt

Viruses are a common threat to cellular life, not the least to bacteria and archaea who constitute the majority of life on Earth. Consequently, a variety of mechanisms to resist virus infection has evolved. A recent discovery is the adaptive immune system in prokaryotes, a type of system previously thought to be present only in vertebrates. The system, called CRISPR-Cas, provide sequence-specific adaptive...

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Identifiers

PMID: 25868999
DOI: 10.1016/j.biochi.2015.03.025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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