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Clinical applications of CRISPR‐based genome editing and diagnostics

2 Jan 2019

Abstract excerpt

Clustered regularly interspaced short palindromic repeats (CRISPR)-driven genome editing has rapidly transformed preclinical biomedical research by eliminating the underlying genetic basis of many diseases in model systems and facilitating the study of disease etiology. Translation to the clinic is under way, with announced or impending clinical trials utilizing ex vivo strategies for anticancer immunotherapy or...

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PMID: 30600536
DOI: 10.1111/trf.15126

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