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Article

Diversity, evolution, and therapeutic applications of small RNAs in prokaryotic and eukaryotic immune systems.

Physics of life reviews - 1 Mar 2014

Cooper Edwin L, Overstreet Nicola

Abstract excerpt

Recent evidence supports that prokaryotes exhibit adaptive immunity in the form of CRISPR (Clustered Regularly Interspersed Short Palindromic Repeats) and Cas (CRISPR associated proteins). The CRISPR-Cas system confers resistance to exogenous genetic elements such as phages and plasmids by allowing for the recognition and silencing of these genetic elements. Moreover, CRISPR-Cas serves as a memory of past...

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Identifiers

PMID: 24286719
DOI: 10.1016/j.plrev.2013.11.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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