Clinical features, molecular pathology, and immune microenvironmental characteristics of acral melanoma.

Abstract excerpt

Acral melanoma (AM) has unique biology as an aggressive subtype of melanoma. It is a common subtype of melanoma in races with darker skin tones usually diagnosed at a later stage, thereby presenting a worse prognosis compared to cutaneous melanoma. The pathogenesis of acral melanoma differs from cutaneous melanoma, and trauma promotes its development. Compared to cutaneous melanomas, acral melanomas have a...

Topics

• Humans
• Melanoma
• Mutation
• Pathology, Molecular
• Skin Neoplasms
• Tumor Microenvironment
• Melanoma, Cutaneous Malignant