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Article

Translational pathology, genomics and the development of systemic therapies for acral melanoma.

Seminars in cancer biology - 1 Apr 2020

Chen Yian Ann, Teer Jamie K, Eroglu Zeynep, Wu Jheng-Yu, Koomen John M, Karreth Florian A, Messina Jane L, Smalley Keiran S M

Abstract excerpt

Acral melanomas arise on the non-hair bearing skin of the palms, soles and in the nail beds. These rare tumors comprise 2-3 % of all melanomas, are not linked to UV-exposure, and represent the most frequent subtype of melanomas in patients of Asian, African and Hispanic origin. Although recent work has revealed candidate molecular events that underlie acral melanoma development, this knowledge is not yet been...

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Identifiers

PMID: 31689494
DOI: 10.1016/j.semcancer.2019.10.017
PMCID: PMC7771370

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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