Article
Association of IGF-1 CA(n) and IGFBP3 rs2854746 Polymorphisms with Endometrial Polyp Risk.
BioMed research international - 1 Jan 2018
Doria Pedro Leopoldo Silva, Moscovitz Thomas, Tcherniakovsky Marcos, Fernandes Cesar Eduardo, Pompei Luciano Melo, Wajman Milton, Nimwegen Angela Van, Haimovich Sergio
Abstract excerpt
INTRODUCTION: Insulin-like growth factor 1 (IGF-1) is a peptide growth factor that promotes cell proliferation and inhibits apoptosis. The bioavailability of IGF-1 is regulated by the insulin-like growth factor binding protein 3 (IGFBP3). Genetic variations influence the levels of IGF-1 and IGFBP3. The purpose of this study was to examine the association of polymorphisms IGF-1 CA(n) and IGFBP3 rs2854746 with risk...
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