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IGF1 polymorphisms and colon cancer risk in Tunisian population.

La Tunisie medicale - 1 Jan 2020

Dhifallah Haifa, Aissi Sana, Njima Manel, Zakhama Abdelfatteh, Kenani Abderraouf

Abstract excerpt

BACKGROUND: Insuline-like growth factor I (IGF1) is a peptide growth factor that promotes cell proliferation and inhibits apoptosis. AIM: To examine the association of genetic variants in IGF1 (rs12423791, rs1019731, rs5742632, rs2033178 and rs2373722) with risk of colon cancer in Tunisia. METHODS: The study included 76 formalin-fixed paraffin embedded primary colorectal carcinomas and paired normal colon. The...

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PMID: 32395779

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