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Analysis of antifungal resistance genes in Candida albicans and Candida glabrata using next generation sequencing

10 Jan 2019

Abstract excerpt

INTRODUCTION/OBJECTIVES: An increase in antifungal resistant Candida strains has been reported in recent years. The aim of this study was to detect mutations in resistance genes of azole-resistant, echinocandin-resistant or multi-resistant strains using next generation sequencing technology, which allows the analysis of multiple resistance mechanisms in a high throughput setting. METHODS: Forty clinical Candida...

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PMID: 30629653
DOI: 10.1371/journal.pone.0210397

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