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Article

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance.

Journal of visualized experiments : JoVE - 28 Dec 2017

Biswas Chayanika, Chen Sharon C-A, Halliday Catriona, Martinez Elena, Rockett Rebecca J, Wang Qinning, Timms Verlaine J, Dhakal Rajat, Sadsad Rosemarie, Kennedy Karina J, Playford Geoffrey, Marriott Deborah J, Slavin Monica A, Sorrell Tania C, Sintchenko Vitali

Abstract excerpt

Candida glabrata can rapidly acquire mutations that result in drug resistance, especially to azoles and echinocandins. Identification of genetic mutations is essential, as resistance detected in vitro can often be correlated with clinical failure. We examined the feasibility of using whole genome sequencing (WGS) for genome-wide analysis of antifungal drug resistance in C. glabrata. The aim was torecognize...

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Identifiers

PMID: 29364212
DOI: 10.3791/56714
PMCID: PMC5908403

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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