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Article

A novel copy number variation in CATSPER2 causes idiopathic male infertility with normal semen parameters

30 Nov 2018

Abstract excerpt

STUDY QUESTION: Are genetic abnormalities in CATSPER (cation channel of sperm) genes associated with idiopathic male infertility with normal semen parameters and, if so, how do they affect male fertility? SUMMARY ANSWER: A novel copy number variation (CNV) in CATSPER2 causes idiopathic male infertility with normal semen parameters by disrupting the ability of sperm to penetrate viscous media, undergo...

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PMID: 30629171
DOI: 10.1093/humrep/dey377

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