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Article

Mutational analysis of head and neck squamous cell carcinoma stratified by smoking status

10 Jan 2019

Abstract excerpt

Smoking has historically been recognized as a negative prognostic factor in head and neck squamous cell carcinoma (HNSCC). This study aimed to assess the mutational differences between heavy smokers (>20 pack years) and never smokers among the HNSCC patients within The Cancer Genome Atlas (TCGA). Single nucleotide variation and copy number aberration differences between heavy smokers and never smokers were...

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PMID: 30626742
DOI: 10.1172/jci.insight.123443

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