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Clinical relevance of circulating tumor DNA assessed through deep sequencing in patients with metastatic colorectal cancer

21 Dec 2018

Abstract excerpt

Because circulating tumor DNA (ctDNA) studies focusing on only one or a few genes to monitor the disease progress or treatment response are unlikely to find its clinical significance, the development of cell-free DNA (cfDNA) panel covering hundreds of mutation hot spots is important for the establishment of clinically practical ctDNA detection system. We enrolled 101 patients with metastatic colorectal cancer...

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PMID: 30575318
DOI: 10.1002/cam4.1913

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